Anhang / Literatur / Autorenhinweis

In Deutschland zugelassene Produkte auf Dimeticonbasis
Handelsname Dimeticon-Konzentration Weitere Substanzen Daten zur Wirksamkeit publiziert 1 Wirksamkeit 2
Linicin® Lotion unbekannt Tocopheryl acetate, Prunus dulcis-Öl, Prunus armeniaca-Öl nein unbekannt
Dimet® Dodecanol, Isopropanol, Parfümöl nein unbekannt
Paramitex® Lotio 4 % Wasser, Kokosfett, Decansäure, Dodecansäure, Sorbitanstearat, Sucrose-cocoat, Glycerin, Carbomer Interpolymer Typ A, Parfumöl, Kokosmilch, Methylhydroxybenzoat, Propylhydroxybenzoat, Kaliumhydroxid nein unbekannt
EtoPril® 4% Cyclomethicone ja 70 – 92%
NYDA® 92 % mittelkettige Triglyceride, Jojobawachs ja 97 %
Jacutin® Pedicul Fluid 100 % nein unbekannt

1 Publikation mindestens einer Studie mit einem adäquaten Studiendesign in einer international durch Gutachter beurteilten Fachzeitschrift (nicht Abstrakt oder Poster)
2 nach Daten aus lege artis durchgeführten und publizierten klinischen Studie
3
Gesamtkonzentration eines niedrig viskösen plus eines höher viskösen Dimeticons

Weiterführende Literatur

Bauer E, Jahnke C, Feldmeier H. Seasonal fluctuations of head lice infestation in Germany. Parasitol Res 2009; 104(3):677-681.

Boutellis A, Medlannikov O, Bilcha KD, Ali J, Campelo D, Barker SC et al. Borrelia recurrentis in Head Lice, Ethiopia. Emerg Infect Dis 2013; 19:796-798.

Burgess IF, Brown CM, Lee PN. Treatment of head louse infestation with 4% dimeticone lotion: randomised controlled equivalence trial. BMJ 2005; 330:1423­1426.

Burgess IF, Lee PN, Brown CM. Randomised, controlled, parallel group clinical trials to evaluate the efficacy of isopropyl myristate/cyclomethicone solution against head lice. Pharmac J 2008; 280:371-375.

Burgess IF. The mode of action of dimeticone 4% lotion against head lice, Pediculus capitis. BMC Pharmacol 2009; 9(3):doi:10.1186/1471-2210-9-3.

Burgess IF, Brunton ER, Burgess NA. Clinical trial showing superiority of a coconut and anise spray over permethrin 0.43% lotion for head louse infestation, ISRCTN96469780. Eur J Pediatr 2010; 169:55-62.

Burgess IF, Kay K, Burgess NA, Brunton ER. Soya oil-based shampoo superior to 0.5% permethrin lotion for head louse infestation. Medical Devices: Evid Res 2011; 4(4):35-42.

Canyon DV, Spear RC, Muller R. Spatial and kinetic factors for the transfer of head lice (Pediculosis capitis) between hairs. J Investig Dermatol 2002; 119:629-631.

Chosidow O, Giraudeau G, Cottrell J, Izri A, Hofmann R, Mann SG et al. Oral Ivermectin versus Malathion Lotion for Difficult-to-Treat Head Lice. New England J Med 2010; 362(10):896-905.

Downs AMR, Stafford KA, Coles GC. Head lice: Prevalence in schoolchildren and insecticide resistence. Parasitol Today 1999; 15:1-3.

Durand R, Millard B, Bouges-Michel C, Bruel C, Bouvresse S, Izri A. Detection of Pyrethroid resistance gene in head lice in schoolchildren from Bobigny, France. J Med Entomol 2007; 44:796-797.

Elston DM. Drug-Resistant Lice. Arch Dermatol 2003; 139:1061-1064.

Feldmeier H. Pediculosis capitis - Aktueller Kenntnisstand Epidemiologie, Diagnose und Therapie. Kinder- und Jugendmedizin 2012; 5:308-313.

Feldmeier H, Jahnke C. Kopflausinfestationen - ein Kompendium. Stuttgart: Thieme, 2010.

Feldmeier H. Lice as vectors of pathogenic microorganisms. In: Heukelbach J, editor. Management and Control of Head Lice Infestation. Bremen: UNIMED-Verlag, 2010: 132-135.

Feldmeier H. Pediculosis capitis: New insights into epidemiology, diagnosis and treatment. Europ J Clin Microbiol Infect Dis 2012; 31:2105-2110.

Feldmeier H, Jahnke C. Pediculosis capitis. Epidemiologie, Diagnose und Therapie. Pädiatrische Praxis 2010; 76:359-370.

Feldmeier H. Pediculosis capitis: Eine Herausforderung für das Apothekerteam. PTA-Forum 2013; 11:22-26.

Feldmeier H. Treatment of Pediculosis Capitis: A Critical Appraisal of the Current Literature. Am J Clin Dermatol 2014; 15:401-412.

Harris J, Crawshaw JG, Millership S. Incidence and prevalence of head lice in a district health authority area. Commun Dis Public Health 2003; 6(3):246-249.

Heukelbach J, Wilcke T, Winter B, Feldmeier H. Epidemiology and morbidity of scabies and pediculosis capitis in resource-poor communities in Brazil. Br J Dermatol 2005; 153:150-156.

Heukelbach J, Canyon DV, Speare R. The effect of natural products on head lice: in vitro tests and clinical evidence. J Ped Inf Dis 2007; 2:67-76.

Heukelbach J, Pilger D, Oliveira F, Khakban A, Ariza L, Feldmeier H. A highly efficacious pediculocide based on dimeticone: Randomized observer blinded comparative trial. BMC Inf Dis 2008; 8(115):doi:10.1186/1471-2334-8-115.

Heukelbach J, Oliveira FA, Richter J, Häussinger D. Dimeticone-Based Pediculocides: A Physical Approach to Eradicate Head Lice. The Open Dermatol J 2010, 4: 77-81.

Heukelbach J. Management and Control of Head Lice Infestation. Bremen: UNI-MED Verlag, 2010.

Heukelbach J, Canyon DV, Heukelbach-Oliveira F, Muller R, Spear RC. In vitro efficacy of over-the-counter botanical pediculicides against the head louse Pediculus humanus var capitis based on a stringent standard for mortality assessment. Med Vet Entomol 2008; 22:262-274.

Heukelbach J, Sonnberg S, Becher H, Melo I, Speare R, Oliveira FA. Ovicidal efficacy of high concentration dimeticone: A new era of head lice treatment. J Am Acad Dermatol 2011; 64(4):e61-e62.

Jahnke C, Bauer E, Feldmeier H. Pediculosis capitis im Kindesalter: epidemiologische und sozialmedizinische Erkenntnisse einer Reihenuntersuchung von Schulanfängern. Gesundheitswesen 2008; 70:667-673 .

Jahnke C, Bauer E, Hengge U, Feldmeier H. Accuracy of diagnosis of pediculosis capitis: visual inspection versus wet combing. Arch Dermatol 2009; 145:309-313.

Kristensen M, Knorr M, Rasmussen AM, Jespersen JB. Survey of permethrin and malathion resistance in human head lice populations from Denmark. J Med Entomol 2006; 43:533-538.

Kurt O, Balcioglu C, Burgess IF, Limoncu ME, Girginkardesler N, Tabak T et al. Treatment of head lice with dimeticone 4% lotion: comparison of two formulations in a randomised controlled trial in rural Turkey. BMC Public Health 2009; 9:441.

Laguna MF, Risau-Gusman S. Of lice and math: using models to understand and control populations of head lice. Plos ONE 2011; 6(7):doi:10.1371/journal.pone.0021848; e21848.

Lapeere H, Brochez L, Verhaeghe E, Vander-Stichele RH, Remon JP, Lambert J et al. Efficacy of products to remove eggs of Pediculosis humanus capitis (Phthiraptera: Pediculidae) from the human hair. J Med Entomol 2014; 51(2):400-407.

Lesshafft H, Baier A, Guerra H, Terashima A, Feldmeier H. Prevalence and risk factors associated with pediculosis capitis in an impoverished urban community in Lima, Peru. J Glob Infect Dis 2013; 5(4):138-142.

Menegaux F, Baruchel A, Bertrand Y, Lescoeur B, Leverger G, Nelken B et al. Household exposure to pesticides and risk of childhood leukaemia. Occup Environment Med 2006; 63(2):131-134.

Mumcuoglu KY, Friger M, loff- Uspensky I, Ben- Ishai F, Miller J. Louse comb versus direct visual examination for the diagnosis of head louse infestation. Pediatric Dermatol 2001; 18:9-12.

Nair B. Final report on the safety assessment of stearoxy dimethicone, dimethicone, methicone, amino bispropyl dimethicone, aminopropyl dimethicone, amodimethicone, amodimethicone hydroxystearate, behenoxy dimethicone, C24-28 alkyl methicone, C30-45 alkyl methicone, C30-45 alkyl dimethicone, cetearyl methicone, cetyl dimethicone, dimethoxysilyl ethylenediaminopropyl dimethicone, hexyl methicone, hydroxypropyldimethicone, stearamidopropyl dimethicone, stearyl dimethicone, stearyl methicone, and vinyldimethicone. Int J Toxicol 2003; 22:11-35.

Richling I, Böckeler W. Lethal effects of treatment with a special dimeticone formula on head lice and house crickets (Orthoptera, Ensifera: Acheta domestica and Anoplura, Phthiraptera: Pediculus humanus). Arzneim -Forsch/Drug Res 2008; 58:248-254.

Rukke B.A., Birkemoe T, Soleng A, Heggen-Lindstedt H, Ottesen P. Head lice prevalence among households in Norway; importance of spatial variables and individual and household characteristics. Parasitol 2011; 138:1296-1304.

Sendzik J, Stahlmann R. Arzneimittel gegen Kopflausbefall.Toxikologie und Wirksamkeit. MMP 2005; 28(5):167-172.

Speare R, Buettner PG. Head lice in pupils of a primary school in Australia and implications for control. Int J Dermatol 1999; 38:285-290.

Speare R, Thomas G, Cahill C. Head lice are not found on floors in primary school classrooms. Australian New Zealand J Public Health 2002; 26(3):208-211.

Speare R, Cahill C, Thomas G. Head lice on pillows, and strategies to make a small risk even less. Int J Dermatol 2003; 42:626-629.

Strycharz JP, Lao AR, Alves A, Clark JM. Ovicidal Respone of NYDA formulations on the human head louse (Anoplura: PEdiculidae) using a hair tuft bioassay. Entomol Soc America 2012.

Tomalik-Scharte D, Lazar A, Meins J, Bastian B, Ihrig M, Wachall B et al. Dermal absorption of permethrin following topical administration. Eur J Clin Pharmacol 2005; 61(5-6):399-404.

 

Autoren:

Prof. Dr. med. Hermann Feldmeier
Institut für Mikrobiologie und Hygiene, Campus Benjamin Franklin, Charité Universitätsmedizin, Berlin

Dr. Claudia Jahnke
Stadt Braunschweig, Fachbereich Soziales und Gesundheit, Abteilung Jugendärztlicher Dienst